flue-lined reaction vessel
设备型号：PTFE-Lined Reactor Series设计标准：GB/T 25025-2019《搪玻璃设备》 | ASME BPE (生物制药设备规范)
设备型号：PTFE-Lined Reactor Series设计标准：GB/T 25025-2019《搪玻璃设备》 | ASME BPE (生物制药设备规范)
PTFE-Lined Reactor Technical Specification
Model: PTFE-Lined Reactor Series
Design Standards: GB/T 25025-2019 (Glass-Lined Equipment) | ASME BPE (Bioprocessing Equipment)
I. Material Configuration
Component | Material Options | Key Properties |
Base Shell | Q235-B / 304 / 316L Stainless Steel | Structural layer, mechanical strength ≥200 MPa |
Lining Layer | Polytetrafluoroethylene (PTFE) | Thickness: 2.5~4.0mm, purity ≥99.9%, porosity-free sintering process |
Transition Layer | PFA (Perfluoroalkoxy) | Thermal expansion compensation between PTFE and metal (optional) |
Sealing System | PTFE-encapsulated O-rings + Flexible Graphite Packing | Temp. range: -196℃~250℃, Pressure: 0.6MPa (static)/0.4MPa (dynamic) |
Note: For highly permeable media (e.g., hydrofluoric acid), upgrade to PCTFE (Polychlorotrifluoroethylene) or ETFE (Ethylene Tetrafluoroethylene) coating.
II. Structural Design
Loose Lining: PTFE sheets welded & inserted into shell (for atmospheric/low-pressure vessels)
Compression Lining: PTFE powder molded/sintered → thermally shrunk onto metal shell (pressure rating ≤0.8MPa)
Isostatic Molding (Premium): PTFE suspension sprayed + sintered, seamless, vacuum resistance -0.098MPa
Assembly | Design Features |
Agitation System | Anchor/paddle type + PTFE-clad 316L shaft, dual mechanical seals |
Heat Exchange | Jacket (steam/thermal oil) or PTFE-lined coil, heat transfer coefficient: 60~100 W/(m²·K) |
Flange Connections | DIN/ANSI standard, PTFE flanged seal, anti-leakage |
Sight Glass/Manway | Tempered borosilicate glass + PTFE gasket, pressure resistance: 0.4MPa |
III. Core Advantages
▶ Extreme Corrosion Resistance
Compatible Media:
Strong acids: Conc. H₂SO₄ (98%), HCl (37%), HNO₃ (68%), HF (40%)
Strong alkalis: NaOH (50%), liquid ammonia
Organic solvents: Benzene, chloroform, ethyl acetate
Performance: Outperforms Hastelloy C276, service life ≥10 years (acidic environments)
▶ High Purity & Contamination Prevention
PTFE contact angle >110°, non-stick surface
Complies with FDA 21 CFR 177.1550 (food/pharmaceutical grade)
▶ Broad Temperature Tolerance
Operating Range: -50℃ (cryogenic) ~ +200℃ (steam heating)
Withstands >5,000 thermal cycles (-50℃↔200℃) without delamination
▶ Cost Efficiency
Comparison Item | PTFE-Lined Reactor | Hastelloy Reactor |
Equipment Cost | ¥200,000~500,000 | ¥800,000~2M+ |
Maintenance Frequency | 3~5 years | 1~2 years |
Part Replacement | Localized repair | Full vessel replacement |
IV. Typical Applications
Fine Chemicals: Nitration/sulfonation, chloride synthesis
Pharmaceuticals: API intermediate crystallization, high-purity electrolyte solutions
Hydrometallurgy: Precious metal extraction, acid leaching
Environmental: Waste acid recovery, fluoride-containing wastewater treatment
V. Technical Parameters
Parameter | Standard Range | Custom Options |
Volume | 50L ~ 20,000L | Up to 30,000L |
Design Pressure | -0.1 ~ 0.8 MPa | 1.0 MPa (compression lining) |
Surface Roughness (Ra) | ≤0.8μm | ≤0.4μm (PFA polished) |
Anti-static Design | Embedded copper mesh (optional) | ATEX certification |
Quality Assurance System
Testing Standards:
Lining thickness UT (ISO 21809-2)
Spark testing (≥5kV/mm)
100% Helium leak detection (≤1×10⁻⁹ mbar·L/s)
Document Note: This specification can be supplemented with corrosion resistance data and design calculations based on specific process conditions. Supports EPC project integration.
For detailed engineering parameters, please provide operational data (media composition, temperature/pressure profiles, etc.).
Nozzle 管口 | Connection standard 连接尺寸 | Application用途 |
a | / | Manhole 人孔 |
b | HG/T20592-2009 | Agitator hole 搅拌孔 |
c | HG/T20592-2009 | Temperature hole 温度计口 |
d | HG/T20592-2009 | Discharge hole 排净口 |
e | HG/T20592-2009 | Reserve hole 备用口 |
f | HG/T20592-2009 | Pressure gauge 压力表口 |
S1-2 | / | Sight glass hole 视镜口 |
H1-4 | HG/T20592-2009 | Jacket inlet and outlet hole 夹套进出口 |
K1-2 | HG/T20592-2009 | Reserve hole 备用口 |
m | Inner screw, G1/2” | Jacket vent hole 气体出口 |